Susie Chang was the senior criminalist of the Boston Police Department's crime laboratory.

In "Class Action Satisfaction", it was revealed that she was dating a morgue technician, Alex Simmons, whom she met at a nudist retreat. They had been keeping it a secret but revealed it to Dr. Maura Isles anyway, saying that there seemed to be no policies against coworkers dating.

She also admitted that Dr. Maura Isles was one of her heroes.

She has described herself as having a very physical memory; when circumstances required her to take point in an investigation, she made various dioramas to explain her reasoning.

Chang was killed in "Misconduct Game" by a blow to the head after she had left a crime scene. During the investigation, it was revealed that Chang's death was part of a complex plan to frame the forensics department for poor handling of a recent case, but the subsequent investigation exposed the killer's true agenda.

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